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DC Field | Value | Language |
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dc.contributor.author | Muhuri, Sudipto | - |
dc.contributor.author | Shagolsem, Lenin | - |
dc.contributor.author | Rao, Madan | - |
dc.date.accessioned | 2011-12-15T05:27:22Z | - |
dc.date.available | 2011-12-15T05:27:22Z | - |
dc.date.issued | 2011-09 | - |
dc.identifier.citation | Physical Review E, 2011, Vol.84, 031921 | en |
dc.identifier.issn | 1539-3755 | - |
dc.identifier.issn | 1550-2376 (Online) | - |
dc.identifier.uri | http://hdl.handle.net/2289/4206 | - |
dc.description | Open Access | en |
dc.description.abstract | We study a minimal lattice model which describes bidirectional transport of “particles” driven along a onedimensional track, as is observed in microtubule based, motor protein driven bidirectional transport of cargo vesicles, lipid bodies, and organelles such asmitochondria. Thisminimal model, a multispecies totally asymmetric exclusion process (TASEP) with directional switching, can provide a framework for understanding the interplay between the switching dynamics of individual particles and the collectivemovement of particles in one dimension. When switching is much faster than translocation, the steady-state density and current profiles of the particles are homogeneous in the bulk and are well described by mean-field (MF) theory, as determined by comparison to a Monte Carlo simulation. In this limit, we can map this model to the exactly solvable partially asymmetric exclusion-process (PASEP) model. Away from this fast switching regime the MF theory fails, although the average bulk density profile still remains homogeneous. We study the steady-state behavior as a function of the ratio of the translocation and net switching rates Q and find a unique first-order phase transition at a finite Q associated with a discontinuous change of the bulk density.When the switching rate is decreased further (keeping translocation rate fixed), the system approaches a jammed phase with a net current that tends to zero as J ∼ 1/Q. We numerically construct the phase diagram for finite Q. | en |
dc.language.iso | en | en |
dc.publisher | The Americal Physical Society | en |
dc.relation.uri | http://adsabs.harvard.edu/abs/2011PhRvE..84c1921M | en |
dc.relation.uri | http://dx.doi.org/10.1103/PhysRevE.84.031921 | en |
dc.rights | 2011 The American Physical Society | en |
dc.title | Bidirectional transport in a multispecies totally asymmetric exclusion-process model | en |
dc.type | Article | en |
Appears in Collections: | Research Papers (SCM) |
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2011_PhysRevE_V84_p031921.pdf Restricted Access | Restricted access | 355.31 kB | Adobe PDF | View/Open Request a copy |
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